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UK guidance typically recommends: Loading doses of colecalciferol (e.g., total of approximately 300,000 IU over 6-10 weeks) for confirmed deficiency Maintenance therapy with 8002,000 IU daily thereafter Higher doses may be required for malabsorption conditions Before starting high-dose vitamin D, check corrected calcium and renal function

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Note that commercial payers might not adopt all of the same coding changes as Medicare does, and it is impossible to summarize here the effect on their payment policies