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10.1016/j.chembiol.2008.02.010 98 YantL
Bioavailability matters more than the total weight of the ingredient
The activity of sulfiredoxin in RBCs is sufficient to counteract the Prx II hyperoxidation that occurs during elimination of H 2 O 2 molecules resulting from hemoglobin (Hb) autoxidation
Importantly, these findings provide a mechanistic explanation for the limited diagnostic value of circulating zinc measurements and the variable clinical efficacy of nonspecific zinc supplementation, which fail to capture or correct compartment-resolved zinc dysregulation
