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Description
The importance of ECM cleavage in this process is evident from the phenotype of mice lacking metalloproteinases: a lack of MMP11 leads to a decreased periductal collagen content and decreased mammary gland morphogenesis 63

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NOVEL MODEL SYSTEM FOR A SEVERELY COMPROMISED OXIDATIVE STRESS RESPONSE

Sym-015 is a mixture of two humanized IgG1s, Hu9006, and Hu9338, which targets the SEMA domain, preventing the binding of HGF to c-MET [104]
