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Background: There is limited data on the association of regional brain iron estimates, an imaging biomarker of advancing disease, with clinical outcomes after subthalamic nucleus Deep Brain Stimulation (STNDBS) in Parkinson's disease (PD)

Methylcobalamin is a form of vitamin B12

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DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway