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Because vitamins B12 and folate team up and work with each other and the fact that all other vitamins and minerals are affected by their relationship means that you can have any of the MTHFR symptoms that are the direct result of multiple vitamin and mineral deficiencies that cant be resolved by taking a common multivitamin and mineral supplements

Ion Processes 1992, 118119 , 37 70, DOI: 10.1016/0168-1176(92)85058-8154Fourier transform ion cyclotron resonance mass spectrometry: technique developmentsMarshall, Alan G

doi: 10.1016/S0020-7292(03)00079-1

Consequently, it is suggested that TB-500 may contribute to anti-inflammatory potential via these mechanisms