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Zinc oxide, specifically, has been effective in ulcer healing, performing comparably to enzymatic debriding agents for pressure ulcers [544,545,546] and demonstrating effectiveness in diabetic foot ulcers by promoting debridement through zinc oxide-medicated occlusive dressings, outperforming standard hydrocolloid dressings that utilize autodebridement [547]

Copper Toxicity: Although transdermal patches hardly ever cause copper toxicity, you should nevertheless take the recommended dosage as advised on the bottle

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Pierce RC, Bell K, Duffy P, Kalivas PW