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While GAD67 is a hydrophilic cytoplasmic protein, GAD65 undergoes post-translational hydrophobic modifications, which enable it to be anchored on the membrane compartments of the synaptic vesicles (Kanaani et al., 1999, 2002)
Single-cell suspensions were incubated with a rat anti-mouse CD16/CD32 monoclonal antibody (#567021, BD Biosciences), followed by the surface staining on ice for 25 min
TP53 Mutant Acute Myeloid Leukemias comprise Stem-like Cell Enriched Cellular Hierarchy and are Vulnerable to Targeted Protein Degradation of c-MYC
