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Pulsatile GH patterns are important for optimal receptor sensitivity and metabolic effects - continuous GH exposure can lead to receptor downregulation and may have different metabolic consequences than pulsatile patterns

The circadian clock maintains cardiac function by regulating mitochondrial metabolism in mice

Sfyri PP, Yuldasheva NY, Tzimou A, Giallourou N, Crispi V, Aburima A, et al

[DOI] [PubMed] [Google Scholar] 163.Hagen D.M., Ekena J.L., Geesaman B.M., Viviano K.R
