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Result Oxidative stress and low intake of antioxidants would be risk factors for migraine attacks by inducing inflammation

doi: 10.1073/pnas.1534804100 189 ShiX.GaoZ.LinQ.ZhaoL.MaQ.KangY.et al

Copper is an essential cofactor for numerous key enzymes involved in tissue remodeling, including lysyl oxidase (which cross-links collagen and elastin fibers), superoxide dismutase (the primary intracellular antioxidant enzyme), and cytochrome c oxidase (the terminal enzyme of mitochondrial respiration)

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