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Antagonizing the peripheral breakdown of L-DOPA to dopamine also reduces the incidence of dopamine-induced side effects including nausea & vomiting,(an effect mediated by dopamine stimulation of cells in the Chemoreceptor Trigger Zone, which is located on the peripheral side of the blood-brain barrier) as well as dopamine effects on the cardiovascular system
10.1016/j.mce.2013.04.018 Mol
Also, negative role of AtGSTU17 toward drought and salt stresses has been determined by the mutant analysis
& Robbins, PD
