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First, astrocytes protect neurones in the penumbra, and second, after the end of infarct expansion, astrocytes form a peri-infarct barrier very similar to the perilesional barrier in the TBI

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87 Activation and regulation of non-canonical NF-B pathway Most of the non-canonical NF-B receptors belong to the TNFR superfamily, including BAFF-R, CD40, LTR, and receptor Activator of NF-KappaB (RANK), which are associated with the recruitment of different TRAF members and bind to the corresponding ligands as complexes

doi: 10.1016/j.jad.2013.03.029 232 LakhanSEKirchgessnerA
