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Based on the pathological role of macrophages in RA, the use of nanomaterials for the manipulation of macrophages mainly focuses on the early diagnosis and therapy of RA (Table 1)

A comprehensive biomarker panel often includes markers of mitochondrial function, iron metabolism, and neuroinflammation
[Google Scholar] [PubMed] [CrossRef] Zhao NJ, Liao MJ, Wu JJ, Chu KX (2018)

Their findings revealed that intracellular copper ions are key factors in NLRP3 inflammasome assembly and subsequent activation of cytokines such as caspase-1 and IL-1
