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Description
Journal of the Peripheral Nervous System

A.SidhuH.StoufferD

Located in a region of the brain called the epithalamus, the pineal gland regulates the body's sleep/wake cycle, a crucial task that involves the secretion of a hormone called melatonin

It also helps in reversing the imbalance of matrix metalloproteinases (MMP-9) and their inhibitors (TIMP-1), and in preventing epithelial-mesenchymal transition (EMT) through the modulation of Nrf2, NF-B, and TGF-1/Smad2/3 signaling pathways 6
