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The oxidative TME further suppresses NK function by downregulating activating receptors such as NKp30, NKp44, and NKG2D, collectively weakening anti-tumor responses [175]

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The shots usually don't hurt, but some people have a slight stinging sensation

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Tumor cells can develop adaptive mechanisms to resist ferroptosis induction, such as upregulating antioxidant systems or altering iron metabolism pathways

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