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Replacement of DMF with DMSO, dioxane or dimethylacetamide (DMA) has been reported to avoid the formation of this by-product during the linker attachment step 69,72
Similar studies with broccoli have shown that GSTM1 -/- individuals excreted a greater proportion of ingested sulforaphane via mercapturic acid metabolism than GSTM1 +/+ individuals (17, 18)
7 (Suppl 3), 3541, discussion 4233 (2002)
What matters more is the direction of change over time
