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Exogenous oestrogen in combined oral contraceptive pills and hormone replacement therapy directly enhances Candida adherence to mucosal surfaces via oestrogen receptor-mediated upregulation of Candida adhesins

doi: 10.1200/JCO.2017.77.0388 250 HsuCLeeS-HEjadiSEvenCCohenRBLe TourneauCet al

Beyond the immediate nerve injury, the surgical environment itself contributes through associated factors like the intensity of acute postoperative pain, which acts as a potent nociceptive barrage driving central sensitization, and potentially inadequate perioperative analgesia [4]
doi: 10.1164/rccm.201010-1596OC