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A classic in vitro publication indicated that epithalon induced expression of the catalytic subunit of telomerase and increased enzymatic activity in cultures of human fibroblasts, accompanied by telomere elongation

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This process can be further facilitated by peptides such as Thymosin 4, which activates macrophages, thereby promoting infection control and resolution of inflammation (Yu et al., 2025[162]) as shown in Figure 3b(Fig

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