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Archived from the original on July 27, 2020

Here are several tests I analyze routinely for functional B12 deficiencies

27 Indeed, 4 was methylated in the co-crystal structures of both hNNMT and mNNMT (PDB: 5YJF and 5YJI), but the N -methylated product of 4 only showed about 20% inhibition at 30 M

Research in preclinical models has explored its role in NNMT inhibition, NAD+ metabolism, and cellular energetics (pmc.ncbi.nlm.nih.gov, pubmed.ncbi.nlm.nih.gov)
