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By targeting c-Met and TRK-B, 1D228 could inhibit both tumor cell proliferation and tumor angiogenesis resulting in a synergistic anti-tumor effect
Shorter 10-day courses have also shown improved compliance and fewer side effects fewer adverse events (Yang et al., 2024)
The reduction of mitochondrial GSH pools may indirectly contribute to Grx2 impairment and the development of Parkinsons disease
Targeting epigenetic DNA and histone modifications to treat kidney disease
