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10.1016/j.cell.2017.09.021 Cell 138 StoffelN

Half-life also helps to determine the frequency of dosing
Gastroenterology 161 , 81-93 (2021)

Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents
