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2018 Jan 25;9:36

Lysosomes also serve as signaling hubs to monitor the intracellular levels of nutrients and energy by acting as platforms for the assembly of multiple signaling pathways, such as mammalian target of rapamycin complex 1 (mTORC1) and adenosine 5-monophosphate (AMP)-activated protein kinase (AMPK)

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Cyanocobalamin is the common B12 supplement, and while it is not present in nature when in the liver it can be converted to methylcobalamine or adenosylcobalamin, the physiologically active forms of the vitamin