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It is FDA-approved as Carnitor for carnitine deficiency, providing extensive human safety data

This property of PTX is most likely due to its ability to reduce the synthesis of the pro-fibrotic cytokines TGF-1 and PDGF, which are capable of promoting osteogenesis in PD plaque, thus inducing its calcification [21,22,46,62,63,103,104]
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elegans by the antipsychotic and D2-type dopamine receptor antagonist azaperone
