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Architectural features of inactive and active states of class C GPCRs Class C GPCRs are subdivided into four groups based on their specific agonists: calcium-sensing receptor (CaSR), amino acid receptors (including -aminobutyric acid receptors GABA B1 /GABA B2 and metabotropic glutamate receptors (mGluRs), taste receptors (Taste 1 receptors 1-3), and orphan receptors [78]

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