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Description
Extracellular mtDNA can act as a damage-associated molecular pattern (DAMP), triggering the activation of innate immune receptors such as toll-like receptors (TLRs) and inducing the production of type I interferons (IFNs) [131]

doi:10.1371/journal.pone.0255482

A study by Dingwall et al

Supports normal detoxification pathways
