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Despite the renewed interest in the subject, there have been few randomized controlled trials that demonstrate the superiority of l-PRF to conventional techniques in the periodontal and oral surgery literature
Research A 2018 study in The British Journal of Dermatology found that harsh cleansing increased TEWL by 30% , triggering sebum overproduction

In this issue, the already mentioned Tkalcevic and collaborators study may be illustrative (Seveljevic-Jaran et al., 2006
