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Interestingly, in the recently published systematic review by Lisa et al., men with gPRLomas had a better response to DA treatment compared to women PRL normalization was achieved in 55% and significant tumor shrinkage in 91% of men, whereas in 38% and 76% in women, respectively (59)
These free radicals furiously bounce around inside the mitochondria, striking and damaging the delicate mtDNA blueprints
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