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Description
PNC-27 is derived from the p53 proteins HDM-2 binding domain (amino acids 12-26) and is linked to a membrane-penetrating sequence, allowing it to enter and act on cancer cell membranes

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Tumor-associated macrophages (TAMs) are found at high concentrations in the ascites of patients with OC due to the induction of monocyte differentiation into TAM by factors such as leukemia inhibitory factor and IL-6 (98)

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