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[DOI] [PMC free article] [PubMed] [Google Scholar] 165.Kong J.S., Yoo S.A., Kim H.S., Kim H.A., Yea K., Ryu S.H., Chung Y.J., Cho C.S., Kim W.U

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Several studies have shown that SDH-deficient cells exhibit increased tumorigenesis and that this increase is reversed by the addition of -KG, supporting the idea that succinate accumulation contributes to tumorigenesis through epigenetic modification 100