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Previously published RNA-seq datasets that were used in the study are available at Zenodo ( 1 , in the Gut cell survey 13 and under GEO accession codes GSE154714 (ref

10.18632/aging.102357 Aging 258 WangY.XuE.MusichP

The product of this reaction is 3-hydroxy-trimethyl-lysine which is converted to 4-trimethylaminobutyraldehyde and glycine by a reaction catalyzed by 3-hydroxy-trimethyl-lysine aldolase

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