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Description
Contact with the antigen for which a given B cell is specific leads to its activation and transformation into a plasma cell, which synthesizes immuno-globulin and releases it into the circulation
All patients in the study received an initial treatment of 500 g methylcobalamin IM every other day for ten doses followed by 500 g oral methylcobalamin three times a day thereafter

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J Cereb Blood Flow Metab 35(5):747750
