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Others believe that there may be some defect in hair formation, producing defective sebaceous glands, which might partially explain its physical association with hair follicles

10.1080/17425255.2017.1251903 155 TangS.LiuJ.LiF.YanY.LongX.FuY
In cellular models of ALS the RNA processing gets severely impaired upon oxidative stress, in turn causing the mis-localization of TDP-43 and FUS ( Another major factor contributing to the pathophysiological mechanisms in ALS is excitotoxicity, triggered by excessive postsynaptic glutamate receptor stimulation

Mathisen M, Kantarjian H, Jabbour E, Garcia-Manero G, Ravandi F, Faderl S, Borthakur G , Cortes J, Quintas-Cardama A
