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Additional research is necessary to validate and deepen our comprehension of BA's function in modulating the association between gut microbiota and the risk of CVD

Clin Gastroenterol Hepatol

Therefore, TMAO can aggravate atherosclerosis formation by affecting the metabolism of bile acid and cholesterol

These pathogens possess choline TMA-lyase activity, enabling the conversion of dietary choline into trimethylamine (TMA), a precursor to TMAO, and exhibit invasive capabilities that allow them to enter and persist within vascular tissues
