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Description
ERK: extracellular-regulated kinase
The Grx-SG intermediate is cleaved by a GSH molecule, resulting in reduced Grx and GSSG, which is subsequently reduced by GR [150] (Figure 3)
The dephosphorylation is catalyzed by extracellular alkaline phosphatase
Using transcriptomic analysis, we find that activation of the p53p21 pathway down-regulates expression of many genes involved in nucleotide metabolism
