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Description
Nanodelivery systems are required to optimise the targeting efficacy
During acute ischemia, cellular hypoxemia switches metabolism from aerobic respiration to anaerobic glycolysis, leading to lactate production, decreased cellular pH, and calcium overload in both cytoplasm and mitochondria
Vaccaro A.R..: The Use of Bone Morphogenetic Proteins in Spinal Applications
Even when encapsulated, NPs can be opsonized by serum proteins and captured by phagocytic cells in the liver and spleen as part of the body's clearance mechanisms
