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Similarly, a decrease in the TMEM175 (Transmembrane protein 175) level causes the accumulation of -syn in neurons, leading to the loss of dopaminergic neurons [29]

The analgesic efficacy of donepezil was also demonstrated in several other CIPN rat models (bortezomib, paclitaxel, and vincristine) and did not alter the viability of cancer cells or the efficacy of anticancer drugs [165]

These proteomes facilitate the uptake of EXOs by associated ligands on dendritic cells (DCs)
