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This is seen with the simultaneous use of rifampin, isoniazid, and ketoconazole
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Studies have found that PFD can resist the loss of E-cadherin, the main intermediary protein of A549 cell epithelial cell transformation induced by TGF-, and pulmonary fibrosis in a rat model of silicosis, indicating that PFD can also inhibit epithelial cell transformation (Zhang Y et al., 2019)
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