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Description
Docetaxel cleaves GSDME via the ROS/JNK/caspase-3 pathway, and its pyroptotic effect can be enhanced by demethylation of the DFNA5 gene, highlighting the role of epigenetic regulation in chemosensitisation [70]
Sustained NAD metabolism support
Notably, studies have begun to directly establish molecular links between oxidative damage and the characteristic mutations found in uterine fibroids
10.1073/pnas.1401155111 Proc
