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GHRH is produced by the hypothalamus and triggers the pituitary gland to produce hGH (or growth hormone), which triggers the production of IGF-1 in the liver

Science 333:850856 Dreyfus C, Laursen NS, Kwaks T, Zuijdgeest D, Khayat R, Ekiert DC, Lee JH, Metlagel Z, Bujny MV, Jongeneelen M, van der Vlugt R, Lamrani M, Korse HJ, Geelen E, Sahin , Sieuwerts M, Brakenhoff JP, Vogels R, Li OT, Poon LL, Peiris M, Koudstaal W, Ward AB, Wilson IA, Goudsmit J, Friesen RH (2012) Highly conserved protective epitopes on influenza B viruses

Drug Interactions Because these peptides influence vascular, inflammatory, and neurological pathways, interactions with anticoagulants, NSAIDs, immunosuppressants, psychiatric medications, and other pharmaceutical agents are possible but largely unexplored

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