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This cardiac injury appears to be not exclusively related to sustained uncontrolled hypertension, as there was no significant increase in systolic blood pressure in awake or anaesthetised mice
In vivo studies in ApoE / mice show that chronic oral PS-NP exposure accelerates atherosclerotic plaque formation via increased smooth muscle cell migration regulated by kinesin family member 15 (KIF15) [101]
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Dhanasekaran, D
