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2.1 Mechanism of action and efficacy of drugs 2.1.1 Riluzole As the first FDA-approved drug for ALS (1995), riluzole has been the cornerstone of pharmacological management for decades

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While the medical community continues to unravel the exact mechanisms behind these invisible illnesses, researchers are increasingly pointing to a critical, overlapping pathophysiology: severe oxidative stress, mitochondrial dysfunction, and the total collapse of the body's natural detoxification pathways
