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For example, during nutrient deprivation or increased energy demand, signaling pathways such as the AMP-activated protein kinase (AMPK) pathway may induce phosphorylation, enhancing the enzyme's activity to promote fatty acid oxidation

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It is converted to fructose by sorbitol-6-phosphate 2-dehydrogenase

doi: 10.1046/j.1524-475X.1996.40404.x 122 HerrickSAshcroftGIrelandGHoranMMcCollumCFergusonM
