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Once a patient is on a maintenance dose, their B12 levels are generally stable, and a single days difference is unlikely to have a clinical impact

It helps maintain mitochondrial membrane potential and prevent the release of pro-apoptotic factors from mitochondria, thereby preserving cell viability (Pang, 2015)

Some researchers hypothesize that immunomodulatory peptides could enhance the tolerance-inducing effects of immunotherapy, though this has not been formally studied