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[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Mafort T.T., Rufino R., Costa C.H., Lopes A.J

[5] The pathophysiology of anaphylaxis and anaphylactoid reactions stems from the effect of histamine on vascular and bronchial smooth muscle leading to cutaneous vasodilation and third-spacing (hives, rash, pruritis), bronchospasm (wheezing), and reduced systemic vascular resistance (tachycardia, hypotension)

doi: 10.1371/journal.pone.0046214
