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10.1016/j.freeradbiomed.2009.08.006 108 SmulikR.DbskiD.ZielonkaJ.MichaowskiB.AdamusJ.MarcinekA.et al (2014)

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In a pioneering study, Lonardo et al

Disc herniation involves both mechanical factors (the displaced disc material) and biochemical factors (inflammation)
