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Description
Is there any recovery time involved
Mice were switched to a HFD with 400 mg/kg diet tamoxifen citrate (Envigo, TD.170935) for the duration of the study in order to induce GLP-1R knockdown
The exceptional in vitro potency is attributed to its mechanism of acting as an allosteric potentiator of HGF binding to c-Met (amplifying an endogenous signal), which produces non-linear dose-response curves
In stroke models, it reduces hippocampal neuron loss, restores memory, and improves motor coordination by modulating gene expression and reducing inflammation
