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The average patient age at diagnosis is 56 years

In the nervous system, Ca 2+ release into the cytosol through the mPTP activates neurotransmitter release by triggering vesicle exocytosis [186, 187]

In: Ackerman AB (ed)

Cell membranes were harvested by centrifugation at 20,000 g for 20 min and the soluble intracellular protein fraction retained before the pellet was washed twice with 1 ml PBS