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Moreover, the regulatory profiles of key central metabolic activities involved in the regulation of the acetyl-CoA/CoA ratio, such as the TCA cycle, the glyoxylate shunt and the acetate metabolism were closely interrelated and exercised a control on the biotransformation efficiency [26, 30, 104] (Fig

By enhancing the stability of antigen peptide-MHC complexes and the intensity of co-stimulatory signals, it effectively improves the capacity of DCs to activate T cells (79)

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