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Description
Lysine residues on histones are acetylated through acetyltransferases, which enables the unbound DNA to undergo transcription
10.4088/JCP.17m11725 J Clin Psychiatry
Scharschmidt TC, Segre JA
500 Many of the genes or loci whose mutations are linked to PD converge on some common pathways, such as vesicular trafficking ( SNCA , VAMP4 , RAB29 ), mitochondrial function ( ALAS1 , PINK1 , MCCC1 ), lysosomal function ( GBA1 , ATP6V01 , GALC ), and the proteostasis network ( BAG3 , DNAJ6 , PRKN ), possibly pointing toward different routes to similar states of cellular dysfunction
