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2017;12(2):e0170900

[129] also reported that high-dose vitamin D3 supplementation (100,000 IU every 2 months for 6 months) failed to improve vascular function markers or reduce fatigue in ME/CFS patients

According to the guidelines of the International Pediatric Sepsis Consensus Conference 104 , neonatal sepsis is defined as a clinical syndrome characterized by the presence of both infection and systemic inflammatory response syndrome (SIRS) and can cause severe neurological complications due to brain infection, as well as secondary hypoxemia resulting from septic shock, pulmonary hypertension and severe lung disease