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Animal data predominates
[DOI] [PubMed] [Google Scholar] Gunning V, Tzafestas K, Sparrow H, Johnston EJ, Brentnall AS, Potts JR, Rylott EL, Bruce NC
Fragmented ECM components (e.g., platelet-derived proteins and proteoglycans) generated during tissue remodeling are recognized by immune cells as DAMPs, further amplifying inflammatory and fibrotic signaling via TLR2/4 [318, 319]
Pharmacogenetic labeling of FDA-approved drugs: a regulatory retrospective
